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Construction of a Database of Secondary Structure Segments and Short Regions of Disorder and Analysis of Their Properties
Database Short Regions
2015/5/27
Prediction of the secondary structure of a protein from its amino acid sequence
remains an important task. Not only did the growth of database holding only
protein sequences outpace that of solved p...
专著信息
书名
Coling, expression, secondary structure charaterization of HMG box 1 of hUBF from E. coli and its binding to DNA
语种
英文
撰写或编译
作者
Wulin Yang,Wangyoong Zeng,Danzhou,Yunyu Shi
第一作者单位
出版社
Biochimic...
pH值和钙离子对尖吻蝮蛇抗血小板凝集素二级结构的影响(Effects of pH Value and Ca2+ Ion on the Secondary Structure of Agkisacutacin from Agkistrodon Acutus Venom)
抗血小板凝集素 二级结构 圆二色谱 拉曼光谱 红外光谱
2010/8/25
尖吻蝮蛇毒中抗血小板凝集素是凝血因子IX/凝血因子X结合蛋白,它具有抗凝血和抑制血小板凝集双重活性。用红外光谱、拉曼光谱和CD谱研究了抗血小板凝集素的二级结构以及pH值和钙离子对其二级结构的影响。用CD谱测得,在水溶液中,抗血小板凝集素的主要骨架构象为β-折叠(26.3%)和α-螺旋(19.6%)结构。拉曼光谱显示,在粉末状态,其α-螺旋含量显著降低。CD谱还表明,抗血小板凝集素在pH值3.0~1...
pH值和金属离子对尖吻蝮蛇抗凝血因子Ⅱ二级结构的影响(The Effects of pH and Metal Ions on the Secondary Structure of Anticogulation Factor Ⅱ Studed by CD Spectroscopy)
抗凝血因子Ⅱ 酸度(pH) 二级结构 圆二色谱
2010/8/25
圆二色谱(CD谱)测量表明,尖吻蝮蛇抗凝血因子Ⅱ(ACF Ⅱ)与抗凝血因子Ⅰ(ACF Ⅰ)的二级结构十分相似,它们的主要骨架构象都为反平行β-折叠和α-螺旋结构。pH值对天然ACF Ⅱ的构象有一定的影响,pH值从3到10增大时,α-螺旋含量逐渐减少,反平行β-折叠含量逐渐增大。钙和其他二价金属离子对ACF Ⅱ的骨架结构没有明显影响。三价稀土离子使ACF Ⅱ的α-螺旋含量升高,同时降低其β-转角和β...
Mechanisms of secondary structure breakers in soluble proteins
secondary structure secondary structure breaker soluble proteins structure prediction amphiphilicity
2010/12/2
Breaking signals of secondary structure put strong limitations on the tertiary structures of proteins. In addition to proline and glycine clusters, which are well-known secondary structure breakers, c...