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The nutritional metabolomics crossroads: how to ensure success for dietary biomarkers
nutritional metabolomics dietary biomarkers
2018/11/12
The application of metabolomics in nutrition research has increased in recent years. Although it holds great promise, there are a number of issues or limitations that urgently need attention to enable...
Nutritional metabolomics and breast cancer risk in a prospective study
breast cancer diet nutrition metabolomics biomarker tocopherol alcohol androgen fat
2018/11/15
Background: The epidemiologic evidence for associations between dietary factors and breast cancer is weak and etiologic mechanisms are often unclear. Exploring the role of dietary biomarkers with meta...
Adequacy of nutritional intake from food and supplements in a cohort of pregnant women in Québec, Canada: the 3D Cohort Study (Design, Develop, Discover)
pregnancy cohort nutrient intakes diet supplements Dietary Reference Intakes (DRIs)
2018/11/15
Background: Assessments of the dietary intakes in various populations suggest that pregnant women have difficulty meeting all their nutritional requirements through diet alone. Few large-scale studies...
Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
anemia determinants inflammation iron malaria micronutrient deficiencies risk factors women women of reproductive age
2018/11/15
Background: Anemia in women of reproductive age (WRA) (age range: 15–49 y) remains a public health problem globally, and reducing anemia in women by 50% by 2025 is a goal of the World Health Assembly.
Adjusting soluble transferrin receptor concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
anemia inflammation iron deficiency nutritional assessment soluble transferrin receptor
2018/11/15
Background: Iron deficiency is thought to be one of the most prevalent micronutrient deficiencies globally, but an accurate assessment in populations who are frequently exposed to infections is impede...
Adjusting retinol-binding protein concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
anemia inflammation meta-analysis nutritional assessment retinol-binding protein vitamin A deficiency
2018/11/15
Background: The accurate estimation of the prevalence of vitamin A deficiency (VAD) is important in planning and implementing interventions. Retinol-binding protein (RBP) is often used in population s...
Nutritional Evaluation and Optimisation in Neonates trial: is the protein-to-energy ratio important?
Nutritional Evaluation Optimisation in Neonates protein-to-energy
2018/12/19
The Nutritional Evaluation and Optimisation in Neonates trial has contributed significantly to our understanding of parenteral nutrition in the extreme preterm neonate (1). I was intrigued by the diff...
The elephant in the room: using nutritional biomarker cutoffs to assess status
elephant nutritional biomarker cutoffs assess status
2018/12/19
The value of a nutritional biomarker rests in its ability to accurately assess the nutritional status of an individual or population. This has both clinical and public health implications. The correct...
Glycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial
inborn errors of amino acid metabolism phenylalanine tyrosine threonine medical food sapropterin dihydrochloride executive function
2018/12/3
Background: To prevent cognitive impairment, phenylketonuria requires lifelong management of blood phenylalanine (Phe) concentration with a low-Phe diet. The diet restricts intake of Phe from natural ...
Early nutritional support for extremely premature infants: what amino acid amount should be given?
nutritional extremely premature infants amino acid amount
2018/11/30
Consistently providing adequate nutrition to extremely preterm infants remains a clinical challenge. This is especially true in early postnatal life, when support is largely dependent on parenteral nu...
Event-rate and delta inflation when evaluating mortality as a primary outcome from randomized controlled trials of nutritional interventions during critical illness: a systematic review
critical illness delta inflation enteral nutrition parenteral nutrition clinical trial mortality nutrition therapy
2018/11/29
Background: There is a lack of high-quality evidence that proves that nutritional interventions during critical illness reduce mortality.
Executive summary: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants—the Pre-B Project
enteral neonatal intensive care unit nutrition parenteral preterm birth
2018/11/28
Preterm birth (infants born at <37 wk of gestational age) is a significant clinical and public health challenge in the United States and globally. No universally accepted practice guidelines exist for...
Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants—the Pre-B Project
enteral nutrition growth nutrient requirements parenteral nutrition preterm birth
2018/11/28
The “Evaluation of the Evidence to Support Practice Guidelines for the Nutritional Care of Preterm Infants: The Pre-B Project” is the first phase in a process to present the current state of knowledge...
Comparing the quality of indicators of nutritional status by receiver operating characteristic analysis or by standardized differences
nutritional status receiver operating characteristic
2016/6/3
The publication of the article by Rice et al (1) in this issue of
the Journal is a good occasion to review the use of the receiver
operating characteristic (ROC) method almost 30 y after it was
int...