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Two Thirds of Forest Walkers with Japanese Cedar Pollinosis Visit Forests even During the Pollen Season
forest walking Japanese cedar pollinosis pollen season recreation activity shinrin-yoku
2010/11/16
Background: The most common type of pollinosis in Japan is Japanese cedar pollinosis (JCP). While forest walking is a common form of recreation for Japanese people, it has been unclear whether forest ...
Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis
diet therapy flavonoid Japanese cedar pollen pollinosis quercetin
2010/11/16
During the entire study period, ocular symptom + medication score for the EMIQ group was significantly lower (p < 0.05) than that of the placebo group. When limited to the period, ocular symptom score...
Effects of Pranlukast Hydrate on Airway Hyperresponsiveness in Non-Asthmatic Patients with Japanese Cedar Pollinosis
airway responsiveness allergic rhinitis leukotriene one airway-one disease pranlukast hydrate
2010/11/16
Background: Recent studies have suggested that allergic rhinitis is closely related to bronchial asthma, reflecting the "one airway-one disease" hypothesis. It is unclear if the effects of pranlukast,...
Biomarkers for Allergen Immunotherapy in Cedar Pollinosis
basophils CD203c cedar pollinosis IgG4 immunotherapy
2010/11/16
To initiate, monitor, and complete effective immunotherapy, biomarkers to predict and visualize the immune responses are needed. First, we need to identify the right candidate for immunotherapy. Secon...
Present Situation of Cedar Pollinosis in Japan and its Immune Responses
cedar pollinosis cedar specific Th memory cell epidemiology natural killer T cell
2010/11/16
Recent observations have suggested significant worldwide increase in the prevalence of allergic rhinitis and cedar pollinosis. In Japan, Japanese cedar (Cryptometria japonica) and Japanese cypress (Ch...
Analysis of Helper T Cell Responses to Cry j 1-Derived Peptides in Patients with Nasal Allergy: Candidate for Peptide-Based Immunotherapy of Japanese Cedar Pollinosis
Cry j 1 immunotherapy nasal allergy peptide Th response
2010/11/16
Our results suggest four Cry j 1-derived peptides (p61-80, p115-132, p206-225 and p337-353) may be considered to be the immunodominant T-cell epitopes of the Cry j 1 molecule, and can be useful for th...
Patterns of Drug Prescription for Japanese Cedar Pollinosis Using a Clinical Vignette Questionnaire
allergic rhinitis guideline Japan physician's practice patterns questionnaires
2010/11/17
Our investigation suggested that, compared to ENTs, GPs and IMs have a lower tendency to concomitantly prescribe drugs for localized treatment such as nasal corticosteroids and eye drops with oral med...
A Randomized Double-Blind Comparative Study of Sublingual Immunotherapy for Cedar Pollinosis
Japanese cedar placebo-controlled study QOL seasonal allergic rhinitis
2010/11/17
Background: Seasonal allergic rhinitis (SAR) induced by Japanese cedar pollen is a substantial problem in Japan. Sublingual immuno-therapy (SLIT) is safer than conventional antigen-specific immunother...
Anti-IgE Antibody Therapy for Japanese Cedar Pollinosis: Omalizumab Update
anti-IgE therapy asthma immunotherapy omalizumab seasonal allergic rhinitis
2010/11/17
Seasonal allergic rhinitis (SAR) induced by Japanese cedar pollens is a substantial problem in Japan. Omalizumab, a novel humanized monoclonal anti-immunoglobulin E (IgE) antibody, has already been pr...
A 13-year Study of Japanese Cedar Pollinosis in Japanese Schoolchildren
allergy epidemiology IgE Japanese cedar pollinosis month of birth
2010/11/17
Background: Japanese cedar pollen (JCP) sensitization and Japanese cedar pollinosis (JCPS) appear to be increasingly prevalent in younger children. The present study investigated factors affecting JCP...
Enhanced Production of IgE Anti-Japanese Cedar Pollen Specific Antibodies by Peripheral Blood B Cells from Patients with Japanese Cedar Pollinosis
B cells class switching ELISA immobilized anti-CD3 Japanese cedar pollen
2010/11/17
Background: IgE antibodies against Japanese cedar pollen (JCP) play an important role for the pathogenesis of the cedar pollinosis, but the mechanism of their production has been unclear. We explored ...
Effect of Cry-consensus Peptide, a Novel Recombinant Peptide for Immunotherapy of Japanese Cedar Pollinosis, on an Experimental Allergic Rhinitis Model in B10.S Mice
allergic rhinitis Cry j 1 Cry j 2 Japanese cedar pollinosis T-cell epitope
2010/11/18
Cry-consensus peptide markedly inhibited Cry j 1-induced sneezes, eosinophil infiltration, and eosinophil peroxidase (EPO) activity in nasal tissue. Cry-consensus peptide inhibited the production of a...
Relationship between Airborne Cry j 1 and the Onset Time of the Symptoms of Japanese Cedar Pollinosis Patients
Cry j 1 electron spin resonance (ESR) radical immunoassay Japanese cedar (JC) pollinosis pollen information symptom score
2010/11/18
Background: Some patients with Japanese cedar (JC) pollinosis already show pollinosis symptoms before the first day of the pollen season as determined by microscopic pollen counts.
Methods: Airborne ...
Preliminary Study on Japanese Cedar Pollinosis in an Artificial Exposure Chamber (OHIO Chamber)
allergen exposure allergy symptoms artificial exposure chamber intranasal and intraocular pollen count Japanese cedar pollen
2010/11/18
During the initial exposure, all volunteers except one stayed in the chamber for 1 hour without any nasal or ocular symptoms. The number of pollen in the nose and eyes was 249.2 ± 120.9 and 13.6 ± 13....
Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...