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Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial
seminal prostaglandin levels sperm motion characteristics serum hormones young healthy men
2009/2/23
To evaluate the influence of indomethacin and oxaprozin on reproductive function in healthy young men, 34 volunteers with normal semen parameters were recruited. In a randomized double-blind design,...
Evidence for a role of cyclooxygenase（prostaglandin synthetase）and prostaglandins in the sperm acrosome reaction and fertilization
spermatozoa fertilization acrosome reaction cyclooxygenase prostaglandin inhibitor
2009/2/23
Three cyclooxygenase (prostaglandin synthetase) inhibitors, indomethacin, phenylbutazone, and oxyphenbutazone, decreased fertilization in vitro when mixed with capacitated mouse spermatozoa before a...
Prostaglandin dehydrogenase activity of rat and rabbit testicular tissues and accessory glands before and after castration
Prostaglandin dehydrogenase activity rat rabbit testicular tissues
2009/2/20
Rat reproductive tissues contained both 15-hydroxy-prostaglandin dehydrogenase (PGDH) and delta 13-reductase activities, while rabbit tissues exhibited only PGDH activity. In the rat, delta 13-reduc...
Suppression of the proliferative response of the seminal vesicles to testosterone by inhibitors of prostaglandin synthesis. Testosterone, indomethacin, and proliferation in seminal vesicles
seminal vesicles testosterone prostaglandin synthesis
2009/2/19
Effects of indomethacin (1.25 mg/kg) and aspirin (20 mg/kg) on testosterone-induced (0.25 mg/rat), and of indomethacin on dihydrotestosterone-induced (0.25 mg/rat) mitotic activity of the seminal ...
Control of Rat Testicular Prostaglandin Dehydrogenase, 13-Prostaglandin Reductase, and Total Prostaglandin Dehydrogenase Activities
rat testicular prostaglandin dehydrogenase hypophysectomy luteinizing hormone follicle stimulating hormone
2009/2/19
The effects of hypophysectomy and various hormonal treatments on rat testicular prostaglandin dehydrogenase (PGDH), 13-PG reductase, and total PGDH activities were studied in vivo and in vitro. Al...
Prenatal in vivo bulbourethral gland development is not affected by prostaglandin E2 inhibition
Dimethyl sulfoxide indomethacln masculinization morphogenesis
2009/2/13
Investigation of bulbourethral gland (BUG) development is useful to study genitourinary (GU) tract growth and differentiation. Understanding GU tract growth and differentiation is relevant to testin...
Stage and region-specific localization of lipocalin-type prostaglandin D synthase in the adult murine testis and epididymis
lipocalin-type prostaglandin D synthase adult murine testis epididymis
2008/12/25
Lipocalin-type prostaglandin D synthase in semen has been associated with male fertility, although this relationship is not well defined. To gain insight into potential mechanisms, the objective of ...