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Effect of gossypol on testicular testosterone production in vitro
gossypol testicular testosterone production
2009/2/19
Testicular minces were utilized to study the effect of gossypol on testosterone production. Testosterone production was assessed in both control nd gossypol treated groups after 0 to 4 hours incubat...
Effect of Anesthetics on Testosterone Production in Rats
halothane enflurane ether urethan pentobarbital ketamine gonadotropins blood flow
2009/2/18
Changes in testicular vein and peripheral testosterone concentrations in mature rats were monitored during anesthesia with six different agents. Samples taken 2-3 minutes after initial disturbance o...
Estradiol-induced Inhibition of Testosterone Production by Testicular Interstitial Cells Incubated In Vitro
testosterone interstitial cells estradiol testis steroidogenesis
2009/2/18
Testosterone production by testicular interstitial cells incubated in vitro in the presence of 10-8 to 10-6 M 17-estradiol (E2), 17 -estradiol-3-benzoate (E2B), or benzoic acid (B) was examined. Hig...
Does age-associated reduced Leydig cell testosterone production in Brown Norway rats result from under-stimulation by luteinizing hormone?
Aging testis steroids rat
2009/2/18
Previous studies have shown that reductions in Leydig cell testosterone production occur with aging in the Brown Norway rat. The recent observation that changes in luteinizing hormone (LH) pulse i...
Purification and characterization of a lipophilic factor from testicular macrophages that stimulates testosterone production by Leydig cells
Testis macrophage Leydig cell
2009/2/16
Testicular macrophages have been shown to secrete a factor that stimulates testosterone production by Leydig cells. The purpose of this investigation was to purify and characterize this factor. M...
Age-related decreased Leydig cell testosterone production in the brown Norway rat
Aging Leydig cell testosterone LII Brown Norway
2009/2/13
Previous studies have demonstrated that Leydig cell testosterone production diminishes with age in Brown Norway rats. The objective of the studies presented herein was to test the following possible...
Regulation of testosterone production in the adjuvant-induced arthritic rat
testosterone production adjuvant-induced arthritic rat
2009/2/10
Serum testosterone concentrations are reduced in men with rheumatoid arthritis and in rats with adjuvant-induced arthritis, a common model for rheumatoid arthritis. To understand the mechanism res...
Extracellular calcium and luteinizing hormone effects on 22-hydroxycholesterol used for testosterone production in mouse Leydig cells
Extracellular calcium luteinizing hormone testosterone production mouse Leydig cells
2009/2/7
The effect of extracellular calcium on testosterone synthesis in response to luteinizing hormone (LH) or 22-hydroxycholesterol (22-OH-C) by isolated adult mouse Leydig cells was studied. Leydig ce...
Does gonadotropin receptor complex have an amplifying role in cAMP/testosterone production in Leydig cells?
Human chorionic gonadotropin (hCG) luteinizing hormone (LH) Leydig cell purification testis
2009/2/7
The dose-response relationship between luteinizing hormone/human chorionic gonadotropin (LH/hCG)-stimulated biological response and 125I-labeled hCG binding was studied in purified Leydig cells from...
Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side-Chain Cleavage Enzyme（P450scc）During Leydig Cell Aging
Leydig cell cyclic AMP steroidogenesis Brown Norway rat
2008/12/22
Previous studies have shown that the capacity of Leydig cells from aged (21-24-month-old) Brown Norway rats to produce testosterone is reduced from young (4-month-old) levels, and that this is cor...
Chronic Administration of Atrial Natriuretic Peptide Reduces Testosterone Production of Testes in Mice
ANP spermatogenesis testosterone
2008/12/19
The purpose of the present study was to examine the effect of the long-term administration of human atrial natriuretic peptide (ANP) on testosterone production in male mice. Twenty-five mice recei...