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Simon Mitchell has reviewed the evidence supporting the use of lignocaine, an aminoethylamide local anaesthetic with class 1B anti-arrhythmic properties, as adjuvant therapy to the accepted modalit...
The place of lignocaine administration for DCI treatment seems to be well established. The rationale for its use is a putative anti-inflammatory effect of the drug, most probably due to its ability...
Background. Lignocaine improves outcome in animal brain injury models. Cardiac operations often cause postoperative neuro-psychological (NP) impairment. We investigated cerebral protection by ligno...
There are good reasons to believe, from both animal experimental data and human studies, that lignocaine, given alone or in combination with hyperbaric oxygen, should improve the outcome of acute neur...

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