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A study was conducted on the changes in platelet function and platelet count in the Sprague-Dawley rat induced by a bends-producing N2-O2 compression-decompression cycle. In those instances where mild...
The effect of a simulated dive to 8 ATA on platelet kinetics was studied in normal and splenectomized male and normal female rats. Platelet production and consumption was measured in vivo 1 h and 1 da...
Twenty-four young male divers were assigned randomly to 4 treatment groups: Group I received aspirin (325 mg) three times daily; II received dipyridamole (75 mg) three times daily; III received both d...
An apparatus which enables aggregating agents to be added to a stirred suspension of platelets subjected to a pressure of up to 600 ATA is described. The ensuing aggregation reaction is monitored opti...
The mechanisms involved in the interactions between microgasbubbles and platelets are not clear. The platelet aggregatory response to agonist-induced, receptor-mediated stimuli has been studied extens...
Platelet-rich plasma (PRP) was stirred and incubated at 37 degrees C with N2 microbubbles in vitro in the presence and absence of platelet antagonists. The N2 microbubbles acted as a platelet agonist,...
Platelet counts were measured in 10 divers during the course of 4 experimental deep dives (450 and 600 m) and different anticoagulants were tested. The use of sodium citrate as an anticoagulant was as...
The purpose of this study was to test the hypothesis that hyperbaric oxygen (HBO2) may function by modifying the signal transduction pathway of growth factors or their receptors, or both. Studies were...
The aim of the study was to investigate the acute and chronic effects of hyperoxygenation on platelet aggregation and adenosine triphosphate (ATP) release. To observe the acute effects of hyperbaric o...
Platelet-activating factor (PAF) is a phospholipid mediator with potent biological effects on organisms. Some investigators have previously postulated that PAF exerts its effects by producing oxygen f...
Platelet activation has been suggested to play an important role in the pathogenesis of prethrombotic states and thus may be responsible for decompression illness during compressed air (scuba) diving....
A pilot survey of platelet function was performed on 6 patients undergoing hyperbaric oxygen therapy (2.0 ATA O2 for 2 hours, 6 days/week) for prophylaxis against osteoradionecrosis. Blood was drawn i...
This study investigated hyperbaric oxygen (HBO2) and platelet-derived growth factor-BB (PDGF-BB) to determine their combined effects on fibroblasts from rabbit medial collateral ligament (MCL). METHOD...
Microbubbles of nitrogen gas act as a platelet agonist, but the biochemical mechanisms involved in bubble-induced platelet activation are not well known. One characteristic property of a platelet ago...

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