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Since it is proposed that reactive oxygen species (ROS) is involved in the pathogenesis of various diseases, low-molecular weight superoxide dismutase (SOD) mimetic complexes have been intensively stu...
In order to obtain basic information of trace element distribution in the liver of the Formosan squirrel that accumulates Cu at high level, subcellular and molecular weight distributions in this speci...
Copper is an essential micronutrient with numerous cellular functions. Previous studies have demonstrated that copper deficiency in P19 embryonal carcinoma cells by using a copper depletor, bathocupro...
Copper is an essential trace metal. Proteins exploit the unique redox nature of this metal to undertake a series of facile electron transfer reactions using copper as a cofactor in a select number of ...
We examined a removal effect and a removal mechanism of residual chlorine by copper fiber made from copper sticks. A copper fiber of 1.0 g could remove residual chlorine of about 1.0 mg/L (100 mL) for...
Hypocupremia occurred often by long-term administration of copper (Cu) — poor conventional liquid foods in elderly inpatients with cerebrovascular events. Therefore, new enteral liquid foods such as L...
We have analyzed the copper-transporting P-type ATPase (ATP7B) gene responsible for Wilson's disease to provide an explanation for the early onset of acute hepatitis. The ATP7B coding sequence, includ...
It has been revealed that pigmentation based on the oxidative polymerization of 3,4-dihydroxyphenylalanine (dopa) by the action of a copper-containing enzyme, tyrosinase, is suppressed by free oxalic ...
We investigated the in vitro and in vivo effects of metal ions on the activity of an alpha-glucosidase (Saccharomyces sp.). CuSO4, ZnSO4, and VOSO4 significantly inhibited the alpha-glucosidase activi...
We studied trace metals (copper, iron, zinc) in patients with hepatocellular carcinoma (HCC) with special reference to carcinogenesis. 1. High signal intensity on T1-weighted images in magnetic resona...
The biological function of nuclear copper in mammalian cells is poorly understood because little is known about specific binding protein(s) for nuclear copper. We recently purified that p54nrb/Non-POU...
Daily intakes of four essential trace elements (Cu, Fe, Mn, and Zn) in Ukrainian subjects were estimated in relation to the health effects on habitants after the Chernobyl accident. Two hundred and si...
CueO is a multicopper oxidase involved in Cu-homeostasis of E. coli. CueO has the four catalytic copper binding sites, a type 1 Cu, a type 2 Cu and a pair of type 3 Cu's, in a single chain protein mol...
We have investigated the daily nutritional intakes of young women(subjects). The sera of subjects were separated to under molecular weight 50,000 (mw<50,000) and more than 50,000 (mw>50,000) by filter...

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