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A novel combination therapy for treating vancomycin-resistant bacterial infections（图）
万古霉素 耐药细菌感染 联合疗法
2023/6/5
Researchers have developed a novel combination therapy using the anticancer agent mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomyci...
What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells derived in a dish from stem cells, and restore sight?
Signal Transduction and Targeted Therapy | 宋旭教授/赵永云课题组报道核酸适配体高选择性地抑制SARS-CoV-2诱发的炎症反应（图）
四川大学 生命科学学院 冠状病毒
2024/3/5
自2019年底以来，严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)已经在全世界范围内引起了约5.3亿人感染，导致约1800万人死亡。几乎所有感染SARS-CoV-2的死亡患者都被发现是有细胞因子风暴综合症和病毒败血症，过度的炎症反应导致死亡率的增加，因此，防止过度炎症是避免细胞因子风暴综合症的关键。然而，目前，在临床或研究中应用的抗炎药物或免疫调节剂，包括针对炎症细胞因子(sarilu...
Molecular Therapy在线发表了题为Base-edited Cynomolgus Monkeys mimic core symptoms of STXBP1 encephalopathy的研究论文。该研究由中国科学院脑科学与智能技术卓越创新中心（神经科学研究所）、上海脑科学与类脑研究中心、中科院灵长类神经生物学重点实验室孙强研究组/刘真研究组和上海科技大学黄行许研究组合作完成。该研究通...
‘Frameshifting’ therapy for mast cell cancers reduces size, spread
mRNA c-KIT mast cells cancer cell
2021/8/11
A potential new treatment for mast cell cancers reduces the number of mast cells by 'mutating' the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for ce...
周玉峰团队在《Signal Transduction and Targeted Therapy》上发表Covid-19感染的细胞因子风暴信号通路和治疗的长篇综述（图）
COVID-19 周玉峰团队 细胞因子 免疫球蛋白 糖皮质激素
2023/4/17
2021年7月7日，复旦大学生物医学研究院/附属儿科医院周玉峰研究员与英国格拉斯哥大学/深圳大学医学院徐大模教授合作在Signal Transduction and Targeted Therapy杂志上发表了一篇题为The signal pathways and treatment of cytokine storm in COVID-19 的长篇综述。
近日，山西医科大学基础医学院细胞生理学教育部重点实验室祁金顺教授团队与贺培凤教授带领的健康大数据团队进行的校内合作成果，在国际阿尔茨海默病协会（ADI）会刊《Alzheimer's Research & Therapy》（中科院期刊分区2区，影响因子：6.116）发表了题为《Trichostatin A ameliorates Alzheimer's disease-related patholo...
上海交通大学Molecular Therapy 范先群团队揭示lncRNA ROR染色体构象调控葡萄膜黑色素瘤发生新机制（图）
上海交通大学 Molecular Therapy 范先群 团队 lncRNA ROR 染色体 葡萄膜 黑色素瘤 新机制
2019/9/11
最近美国基因和细胞治疗学会官方杂志《Molecular Therapy》发表上海交通大学医学院附属第九人民医院范先群教授团队研究成果“A Cohesin-Mediated Intrachromosomal Loop Drives Oncogenic ROR lncRNA to Accelerate Tumorigenesis”。该研究揭示了长链非编码ROR(lncRNA-ROR)通过形成染色体内环...
A systematic review and meta-analysis of nutrition therapy compared with dietary advice in patients with type 2 diabetes
dietary advice individualized nutrition therapy meta-analysis review type 2 diabetes
2018/11/21
Background: Despite recommendations, many patients with type 2 diabetes receive dietary advice from nurses or doctors instead of individualized nutrition therapy (INT) that is provided by a dietitian.
2018年SPIE光生物调节治疗机制会议（SPIE Mechanisms of Photobiomodulation Therapy XIII）
2018年 SPIE 光生物调节治疗机制 会议
2017/10/26
2018年SPIE光生物调节治疗机制会议（SPIE Mechanisms of Photobiomodulation Therapy XIII）。
In a possible step forward for gene therapy,Stanford researchers made mice glow like fireflies
step forward gene therapy Stanford researchers mice glow fireflies
2017/3/14
Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would car...
2016第12届光生物调节治疗的机制研讨会（Mechanisms of Photobiomodulation Therapy XII）
Photobiomodulation Therapy photobiomodulation
2017/1/17
Conference attendees are invited to attend the BiOS poster session on Sunday evening. Come view the posters, enjoy light refreshments, ask questions, and network with colleagues in your field. Authors...
Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria
hepcidin iron malaria timing of iron supplementation inflammation
2018/11/28
Background: The provision of iron with antimalarial treatment is the standard of care for concurrent iron deficiency and malaria. However, iron that is given during a malaria episode may not be well a...
Dried whole plant Artemisia annua as a novel antimalarial therapy
Artemisia annua Artemisinin Drug resistance malaria antimalarial
2015/1/24
Malaria is one of the worst vector-borne parasitic diseases in the developing world. The World Health Organization (WHO) estimated that 215 million cases of malaria occurred, with >655,000 deaths; hal...
Targeting bacteriolytic therapy of solid tumors with attenuated Salmonella typhimurium
Attenuated salmonella typhimurium avirulent anaerobic bacteria anticancer agent tumor malignant tumor
2014/12/11
Attenuated Salmonella typhimurium, a motile, nonpathogenic facultative anaerobic bacterium, has been demonstrated experimentally as a novel anticancer agent because of its favored growth within tumors...