搜索结果: 1-15 共查到“基础医学 receptor”相关记录16条 . 查询时间(0.096 秒)
Estrogen receptor involvement in the response of human keratinocytes to ultraviolet B irradiation
UVB Estrogen receptor Keratinocytes
2015/5/25
The signaling mechanisms involved in UVB-induced skin cancer are complex and although the scope of this work is inherently limited in focus, the findings may provide insight into how estrogen receptor...
Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus
Soluble-leptin-receptor Autoantibody Systemic lupus erythematosus Depression
2015/9/28
Background: There is some evidence suggesting that leptin and its negative regulator, soluble-leptinreceptor (SLR) may be able to influence inflammatory and autoimmune processes.
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake
NMDA受体 NMDA D-AP-5 杏仁中央核 食物摄取 水摄取
2012/6/28
目的探讨杏仁中央核中的N-甲基-D-天冬氨酸（NMDA）型谷氨酸受体对食物和水摄取的影响。方法不锈钢套管植入雄性Sprague-Dawley大鼠一侧杏仁中央核内，NMDA型谷氨酸受体激动剂原型物NMDA，或选择性NMDA受体拮抗剂D(?)-2-氨基-5-磷酰基戊酸（D-AP-5）微量注射入饱食和含水度正常的大鼠的杏仁中央核内。结果杏仁中央核内注射入8.50，17.00，或34.00 nmol NM...
CONTRIBUTION OF RANKL REGULATION TO BONE RESORPTION INDUCED BY PTH RECEPTOR ACTIVATION IN OSTEOCYTES
RANKL REGULATION CONTRIBUTION
2015/5/21
PTH increases osteoclasts by upregulating RANKL in cells of the osteoblastic lineage, but the precise differentiation stage of the PTH target cell remains undefined. Recent findings demonstrate that P...
Cloning and Transcriptional Activation of the Vitamin D Receptor (Amphibians)1
VDR amphibians cloning evolution
2009/6/30
The vitamin D receptor (VDR), a member of the nuclear receptor superfamily, is an integral part of the body's calcium regulatory system. Mammalian and avian VDR genes were isolated, sequenced and char...
Genetic Variability of the High-affinity IgE Receptor α Subunit (FcεRIα) is Related to Total Serum IgE levels in Allergic Subjects
allergy FCER1A FcεRIα genetic polymorphism IgE omalizumab
2010/11/18
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a ...
Interaction of CpG-Oligodeoxynucleotides with Toll Like Receptor 9 Induces Apoptosis and Modulates Metaloproteinase-2 Activity in Human Intestinal Epithelium
CpG-ODN HT-29 TLR9
2010/4/20
Recent reports have indicated different effects of immunostimulatory sequences containing CpG-Oligodeoxynucleotides (ODN) on various immune cells. However, the exact role of CpG-ODN in the human gut i...
Correlation between Grade in Transitional Cell Carcinoma (TCC) and Expression of Epidermal Growth Factor Receptor (EGFR)
Epidermal growth factor receptor (EGFR) Transitional Cell
2010/4/8
Background: The present study was undertaken to investigate the correlation of Epidermal Growth Factor Receptor (EGFR) expression with grade of Transitional Cell Carcinoma (TCC). Methods: Tumor sample...
Synthesis, development and preclinical comparison of two new peptide based freeze-dried kit formulation 99mTc-EDDA-Tricine-HYNIC-TOC and 99mTc-EDDA-Tricine-HYNIC-TATE for somatostatin receptor positive tumor scintigraphy
99mTc Somatostatin Tyr3-octreotide Tyr3-Octreotate HYNIC Kit formulation
2010/4/7
Somatostatin receptor (sstr) scintigraphy with [111In diethylenetriaminepentaacetic acid]-octreotide ([111In-DTPA]-OC) has became a routine diagnostic procedure in oncology. However, it suffers from s...
Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs
airway hyperresponsiveness bradykinin cationic protein low molecular weight heparin poly-L-lysine 6-keto-PGF1α thromboxane A2
2010/11/26
To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the b...
Effect of histamine H1 receptor antagonists on antigen-induced increase of cough sensitivity in guinea pigs
allergic reaction capsaicin cough sensitivity guinea pig histamine H1 receptor antagonists
2010/11/26
Eosinophilic airway inflammation and increased cough sensitivity without bronchial hyperresponsiveness are the pathologic and physiologic features of bronchodilator-resistant non-productive cough-asso...
Bronchial biopsy and sequential bronchoalveolar lavage in atopic cough: In view of the effect of histamine H1-receptor antagonists
atopic cough atopy bronchial biopsy bronchial lavage bronchoalveolar lavage chronic non-productive cough eosinophils sequential bronchoalveolar lavage
2010/11/25
We have shown that some patients presenting with chronic bronchodilator-resistant non-productive cough have global atopic tendency, airway cough hypersensitivity without non-specific bronchial hyperre...
Recombinant soluble form of the high-affinity IgE receptor α subunit and anti-IgE antibody inhibit IgE synthesis by IgE-expressing B cells through distinct pathways
apoptosis divalent recognition IgE-binding agents IgE-expressing B cells interleukin-6 monovalent recognition
2010/11/24
Background: Both a recombinant soluble form of the high-affinity IgE receptor α subunit (rsFcεRIα) and anti-IgE antibody have been shown to be involved in the regulation of IgE synthesis. However, the...
Association of IgG Fc receptor II with tyrosine kinases in the human basophilic leukemia cell line KU812F
basophilic leukemia cell line IgG Fc receptor II intracellular calcium mobilization signal transduction tyrosine kinase
2010/11/24
The tyrosine kinase inhibitor genistein inhibited intracellular calcium mobilization caused by cross-linking of FcγRII in a dose-dependent manner. Rapid tyrosine phosphorylation after FcγRII cross-lin...
Role of paired Ig-like receptor-B in the humoral immune response
autoimmunity B cell dendritic cell hypersensitivity mast cell Th2 response
2010/11/22
The Ig-like receptors provide positive and negative regulation of immune cells upon recognition of various ligands, thus enabling those cells to respond adequately to extrinsic stimuli. Murine paired ...