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Characteristics of prolactin-modulated LH induction of LH/hCG receptors. Transient inhibition of receptor induction following prolactin exposure
LH luteinizing hormone
2009/2/23
The temporal relationship between exposure to prolactin (PRL) and luteinizing hormone (LH) induction of LH receptors was investigated in hypophysectomized adult male rats. Testicular homogenate me...
Variation in the effect of a nongonadotropic Leydig cell stimulating factor in testicular interstitial fluid after exposure of the testis to a single episode of heat treatment
Variation nongonadotropic Leydig cell testicular interstitial fluid testis
2009/2/23
The activity of a nongonadotropic factor present in rat testicular interstitial fluid and capable of stimulating Leydig cell testosterone production was measured at intervals for 8 weeks after exp...
The effect of delta 9-tetrahydrocannabinol in utero exposure on rat offspring fertility and ventral prostate gland morphology
marihuana testes ventral prostate gland testosterone
2009/2/23
Male rats exposed in utero to delta 9-tetrahydrocannabinol (delta 9-THC) had lower levels of testosterone (T) and luteinizing hormone (LH) prior to puberty (P less than 0.01). At puberty, the levels...
Analysis of human sperm function following exposure to the ionophore A23187. Comparison of normospermic and oligozoospermic men
A23187 sperm motility fertilization ohgozoospermia
2009/2/20
Time exposure photomicrography and interspecific in vitro fertilization techniques have been used to compare the responses to the divalent cation ionophore A23187 of spermatozoa from normal fertile an...
Periodic exposure to a brief light signal stimulates neuroendocrine-gonadal activity in golden hamsters
photoperiodism circadian rhythms hamsters seasonal reproduction neuroendocrine-gon
2009/2/20
The photoperiodic effects of a periodic light pulse on neuroendocrine-gonadal activity in the male golden hamster was examined using a night interruption paradigm. Adult male hamsters that had been ho...
Effects of short-term methylmercury exposure on metallothionein mRNA levels in the testis and epididymis of the rat
short-term methylmercury metallothionein mRNA rat
2009/2/18
Methylmercury (MeHg) is a widespread environmental contaminant that causes reproductive dysfunction in men. Metallothioneins (MTs) are low-molecular-weight proteins that can bind heavy metals and pr...
The development of male reproductive organ abnormalities after neonatal exposure to tamoxifen is genetically determined
Neonate mice strains testicular infarction epididymitis
2009/2/18
Responses of the male reproductive organs to neonatal exposures of tamoxifen (Tx) were examined in seven different strains of mice (A/J, AKR/J, BALB/cAnN, C3H/HeJ, C57BL/6J, DBA/ 2J, and FVB/N). Mal...
Exposure of thawed frozen bull sperm to a synthetic peptide before artificial insemination increases fertility
Enhancement of fertility bovine sperm prosaposin
2009/2/18
We evaluated the effect on fertility of in vitro exposure of thawed frozen bull sperm to synthetic FertPlus peptide prior to artificial insemination (AI). The peptide represented a 60-amino acid s...
Exposure of human, boar, or bull sperm to a synthetic peptide increases binding to an egg-membrane substrate
human boar bull sperm synthetic peptide increases egg-membrane substrate
2009/2/18
We evaluated the effects of in vitro exposure of sperm to synthetic FertPlus peptide, which represents a 60-amino acid sequence within rat prosaposin, using a microwell sperm-binding assay (SBA), ...
Discriminant analysis indicates a single sperm protein（SP22）is predictive of fertility following exposure to epididymal toxicants
Epididymis biomarker
2009/2/17
In a previous study, we found that ethane dimethanesulphonate (EDS) compromised the fertilizing ability of proximal cauda epididymal sperm from the rat within 4 days of exposure, an effect that pers...
Compromised sperm protein phosphorylation after capacitation, swim-up, and zona pellucida exposure in teratospermic domestic cats
Cat sperm teratospermia tyrosine phosphorylation zona pellucida
2009/2/16
Tyrosine phosphorylated proteins recently have been found in mouse and human spermatozoa. Our objectives were to (1) determine if domestic cat spermatozoa also express tyrosine phosphorylated pro...
2,5-hexanedione exposure in the rat results in long-term testicular atrophy despite the presence of residual spermatogonia
Germ cell repopulation Sertoli cell toxicity spermatogonia
2009/2/7
Charles River CD rats (approximate weight, 208 g) were exposed to 1.0% 2,5-hexanedione (2,5-HD) in drinking water for 5 weeks. Rats were killed 27, 60, and 75 weeks after exposure to evaluate the re...
The effect of duration of exposure on the expression of lead toxicity on the male reproductive axis
Lead male reproduction spermatogenesis duration of exposure
2009/2/6
This study assesses the significance of duration of exposure on the expression of lead toxicity on the male reproductive system. Male Wistar rats, 52 days old, were treated with 0.0% or 0.6% lead ac...
Postweaning exposure to gossypol results in epididymis-specific effects throughout puberty and adulthood in rats
Male reproduction sexual development sperm maturation male contraception
2008/12/30
Gossypol, a yellow pigment found in cottonseeds, well known for its antifertility properties in animals, has been used as a contraceptive by men. The aims of this work were to evaluate the effects o...
Prenatal exposure to dexamethasone alters Leydig cell steroidogenic capacity in immature and adult rats
Testis neuroendocrine luteinizing hormone testosterone
2008/12/29
This study examines the effects of prenatal exposure to dexamethasone (DEX) on postnatal testosterone production in male rats. Pregnant female rats were treated on gestation days 14-19 with DEX (1...