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A simple strategy could make first-line antibiotics more effective against resistant bacteria
A simple strategy first-line antibiotics against resistant bacteria
2015/4/30
Researchers have identified a single, simple metric to inform medication regimen design that could bring an entire arsenal of first-line antibiotics back into the fight against drug-resistant pathogen...
Factors Associated with First-Line Antiretroviral Therapy Failure amongst HIV-Infected African Patients: A Case-Control Study
HIV Treatment ART Failure
2013/2/19
Background: Since 2001, anti-retroviral therapy (ART) has been provided to over 75,000 HIV-infected patients at the USAID-Academic Model Providing Access to Healthcare (AMPATH) Partnership in western ...
Coupling of on-Line Pre-Column Oxidative Cleavage and Solid-Phase Enrichment with Liquid Chromatography Using an Eco-Friendly Analytical Procedure to Determine Low Levels of Methotrexate
Cerium (IV) Trihydroxyhydroperoxide HPLC Methotrexate
2013/1/29
A simple, sensitive and precise green high-performance liquid chromatographic method including on-line pre-column oxidation combined by column switching with a short Hypersil ODS analytical column (10...
Influence of Preservation Solutions and Bile on a Human Bile Duct Epithelium Cell Line: An In-Vitro Study
Organ Preservation Liver Transplantation Bile Duct Epithelium In Vitro
2013/1/31
Introduction: Bile duct complications are common after liver transplantation. The impact of preservation solution is unclear. Aim: We investigated the impact of different preservation solutions with a...
Raltitrexed + irinotecan as second-line chemotherapy in elderly patients with advanced colorectal cancer
Colorectal Elderly Irinotecan Second-Line Unresectable
2013/1/30
Aims and Background: Irinotecan is a standard option for relapsed/refractory advanced colo- rectal cancer. Combination with raltitrexed and irinotecan at lower than MTD doses should preserve disease s...
Optimal nonlinear line-of-flight estimation in PET
Artificial neural network emission tomography gamma camera scintillation detector
2010/1/7
The authors consider detection of high-energy photons in positron emission tomography using thick scintillation crystals.Parallax effect and multiple Compton interactions in such
crystals significant...
Optimal nonlinear line-of-flight estimation in PET
Artificial neural network emission tomography gamma camera scintillation detector
2010/1/7
The authors consider detection of high-energy photons in positron emission tomography using thick scintillation crystals.Parallax effect and multiple Compton interactions in such
crystals significant...
Time Dependent Response and the de Almeida-Thouless Line in R 1:2:3 Superconductors
Time Dependent Response the de Almeida-Thouless Line R 1:2:3 Superconductors
2010/1/6
Time Dependent Response and the de Almeida-Thouless Line in R 1:2:3 Superconductors.
Reduction of CPR artifacts in the ventricular fibrillation ECG by coherent line removal
CPR artifacts the ventricular fibrillation ECG coherent line removal
2010/2/25
The localized coherent line removal algorithm reduces CPR-artifacts in VF-ECG, but does not eliminate them. Our SNR-improvements are in the same range as offered by multichannel methods of Rheinberger...
Current computed tomography (CT) scanners, including micro-CT scanners, utilize a point x-ray source. As we target higher and higher spatial resolutions, the reduced x-ray focal spot size limits the t...
DNase γ-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line
DNase γ-dependent -independent apoptotic DNA
2009/12/16
DNA fragmentation is a biochemical hallmark of apoptosis. Several endonucleases, including CAD/DFF40 and endonuclease G, are implicated in DNA fragmentation. DNase γ has also been considered to be one...
Effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and proliferation of HO-8910 cell line of ovarian cancer
3`-azido-3`-deoxythymidine (AZT) reverse transcriptase inhibitor telomerase proliferation ovarian carcinoma cell
2009/4/20
Objective: To study the effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and the proliferation of ovarian cancer cells in vitro. Methods: Telomerase activity was detected by enzyme ...
Analysis of Cisplatin Behavior in a Non-Small Cell Lung Cancer（NSCLC）Cell Line
cisplatin resistance NSCLC intracellular Pt accumulation Pt-DNA adduct
2009/3/23
Cisplatin (CDDP) is an effective anticancer agent that is widely used in the treatment of testicular, ovarian, bladder and lung cancers. However the development of resistance to CDDP by tumor cells is...
Dibutyltin（DBT）Dichloride Inhibits Cytokine Productions in Murine Macrophage Cell Line, J774.1.
dibutyltin macrophages tumor necrosis factor α interleukin-1β real time PCR ELISA
2009/3/23
The immune system is a target of dibutyltin (DBT) intoxication. We evaluated the effects of DBT dichloride in macrophages using the murine macrophage cell line, J774.1. Cultured J774.1 cells were expo...
The Effects of Dibutyltin(DBT)Dichloride on the Viability and the Productions of Tumor Necrosis Factor α and Interleukin-12 in Murine Macrophage Cell Line, J774.1.
dibutyltin macrophages interleukin-10 interleukin-12
2009/3/16
Immunotoxicity is one of toxic effects of dibutyltin(DBT)compounds. In our previous study, the inhibitory effects of DBT on the productions of tumor necrosis a(TNFα)and interleukin-1β in a murine macr...