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A new study finds that a component of aspirin binds to an enzyme called GAPDH, which is believed to play a major role in neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s...
Knowing the subcellular location of a protein is critical to a full understanding of its function, and automated, objective methods for assigning locations are needed as part of the characterizatio...
We describe the Protein Subcellular Location Image Database (PSLID), which collects and structures 2-D through 5-D fluorescence microscope images, annotations, and derived features in a relational ...
Research on the cell and molecular biology of proteins involved in membrane traf®c often requires determination of the effects of various experimental conditions on the subcellular distribution...
There is extensive interest in automating the collection, organization and analysis of biological data. Data in the form of images present special challenges for such efforts. Since fluorescence mi...
After Sequencing: Quantitative Analysis of Protein Localization.
We describe a method of classifying cellular protein localization patterns based on their appearance in uorescence light microscope images. Images depicting cellular protein localization were obtai...
This study was done to compare the effects of bone morphogenetic protein-4 (BMP-4) on mouse embryonic stem cells (ESC) differentiation to erythroid lineage in serum free and serum supplemented media. ...

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